chief cell การใช้

• The parathyroid chief cell is the primary cell of the parathyroid gland.
• Parathyroid chief cells have large amounts of organelles associated with protein synthesis.
• In the stomach, chief cells release pepsinogen.
• Gastric chief cells are primarily activated by ACh.
• The Gastric chief cell start to digest the stomach " post mortem ".
• However the decrease in pH caused by activation of parietal cells further activates gastric chief cells.
• They also secrete parietal and chief cells of the stomach from secreting acid and their digestive enzymes.
• Parathyroid chief cells make up the majority of the parathyroid gland along with adipocytes and oxyphil cells.
• A prime example of this is pepsin, which is secreted in the stomach by chief cells.
• Pepsinogen is activated when chief cells release it into the gastric acid, whose hydrochloric acid partially activates it.
• Gastric lipase is an acidic lipase secreted by the gastric chief cells in the fundic mucosa in the stomach.
• The chief cells secrete pepsinogen in response to gastrin and especially Ach, and ACh also stimulates mucus secretion.
• Low levels of calcium stimulates the release of parathyroid hormone ( PTH ) from chief cells of the parathyroid gland.
• The gastric chief cells of the stomach secrete enzymes for protein breakdown ( inactive pepsinogen, and in infancy rennin ).
• Gastric chief cells are much longer lived and are believed to differentiate from stem cells located higher in the gastric unit in the isthmus.
• Alternatively, acid in the duodenum can stimulate S cells to secrete secretin which acts on an endocrine path to activate gastric chief cells.
• Histamine and gastrin act synergistically as the most important stimulators of hydrochloric acid secretion from parietal cells and stimulators of secretion of pepsinogen from chief cells.
• Cells found in the gastric glands include foveolar cells, chief cells, parietal cells, G cells and enterochromaffin-like cells ( ECLs ).
• The chief cells play a large role in the endocrine system, as they secrete parathyroid hormone ( PTH ), which is involved in calcium homeostasis.
• The "'chief cells "'are found in the basal regions of the gland and release a zymogen  pepsinogen, a precursor to pepsin.